Coordination of Intratumoral Immune Reaction and Human Colorectal Cancer Recurrence
نویسندگان
چکیده
منابع مشابه
Coordination of intratumoral immune reaction and human colorectal cancer recurrence.
A role for the immune system in controlling the progression of solid tumors has been established in several mouse models. However, the effect of immune responses and tumor escape on patient prognosis in the context of human cancer is poorly understood. Here, we investigate the cellular and molecular parameters that could describe in situ immune responses in human colorectal cancer according to ...
متن کاملComment re: Intratumoral immune reaction in human colorectal cancer.
To the Editor: The recent article by Camus and coworkers (1) is in line with their previous reports on immune cell infiltration in colorectal cancer (CRC). They showed the presence of a high density of immune effector cells in tumors of patients without metastases, whereas these cells were absent in the primary tumor or did not have an effector phenotype in metastasized patients (1). Although w...
متن کاملAnastomotic recurrence of colorectal cancer
Local recurrence after radial surgical excision of a large bowel neoplasm is nothing short of a catastrophe, because it heralds the onset of a progressive, painful, debilitating condition which untreated, has an average survival time of 11 months. ' As many patients do not have disseminated disease, death is often slow and attended by considerable morbidity.2 Most local recurrences occur after ...
متن کاملAnastomotic recurrence of colorectal cancer
Local recurrence after radial surgical excision of a large bowel neoplasm is nothing short of a catastrophe, because it heralds the onset of a progressive, painful, debilitating condition which untreated, has an average survival time of 11 months. ' As many patients do not have disseminated disease, death is often slow and attended by considerable morbidity.2 Most local recurrences occur after ...
متن کاملIntratumoral T cells, recurrence, and survival in epithelial ovarian cancer.
BACKGROUND Although tumor-infiltrating T cells have been documented in ovarian carcinoma, a clear association with clinical outcome has not been established. METHODS We performed immunohistochemical analysis of 186 frozen specimens from advanced-stage ovarian carcinomas to assess the distribution of tumor-infiltrating T cells and conducted outcome analyses. Molecular analyses were performed i...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2009
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-08-2654